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Hexestrol 

Cat. No.: HY-B1662 Purity: >98.0%
Handling Instructions

Hexestrol is a nonsteroidal synthetic estrogen. Hexestrol can be used for the research of the diseases caused by estrogen deficiencym, and it also can increase the weight of cattle.

For research use only. We do not sell to patients.

Hexestrol Chemical Structure

Hexestrol Chemical Structure

CAS No. : 84-16-2

Size Price Stock Quantity
10 mM * 1  mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
50 mg USD 50 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Description

Hexestrol is a nonsteroidal synthetic estrogen. Hexestrol can be used for the research of the diseases caused by estrogen deficiencym, and it also can increase the weight of cattle[1][2].

In Vivo

Hexestrol (3 and 6 mg/kg; i.p. once daily for 30 days) has a not significant influence in the ovaries from mice at the dose of 3 mg/kg[2].

Animal Model: Mus musculus (90-120 days, 25-50 g)[2]
Dosage: 3, 6 mg/kg (adopted the same dose used to increase weight gain in cattle)
Administration: I.p. once daily for 30 days
Result: Numerous follicles in different stages of development were found at the dose of 3 mg/kg in the ovaries.
Not detected the corpora lutea (CL) at the dose of 6 mg/kg.
Molecular Weight

270.37

Formula

C₁₈H₂₂O₂

CAS No.

84-16-2

SMILES

CC[[email protected]](C1=CC=C(O)C=C1)[[email protected]](C2=CC=C(O)C=C2)CC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (369.86 mM; Need ultrasonic)

氘代氯仿 : < 1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6986 mL 18.4932 mL 36.9864 mL
5 mM 0.7397 mL 3.6986 mL 7.3973 mL
10 mM 0.3699 mL 1.8493 mL 3.6986 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (9.25 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (9.25 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (9.25 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

HexestrolEstrogen Receptor/ERRnonsteroidalsyntheticestrogenInhibitorinhibitorinhibit

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Hexestrol
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HY-B1662
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