533884-09-2
533884-09-2
Chemical Structure
Erteberel
Synonym(s): LY500307
- CAS No.: 533884-09-2
- Formula:C18H18O3
- Molecular Weight:282.33
IUPAC Name: (3aS,4R,9bR)-4-(4-hydroxyphenyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol
InChIKey: XIESSJVMWNJCGZ-VKJFTORMSA-N
SMILES: OC1=CC=C2C([C@@](CCC3)([H])[C@@]3([H])[C@H](C4=CC=C(O)C=C4)O2)=C1
Biological Activity: Erteberel (LY500307) is a potent and selective estrogen receptor beta (ERβ) agonist with Ki and EC50 of 1.54 nM and 3.61 nM, respectively. Erteberel has anti-tumor activities[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Erteberel | 99.49% | Erteberel (LY500307) is a potent and selective estrogen receptor beta (ERβ) agonist with Ki and EC50 of 1.54 nM and 3.61 nM, respectively. Erteberel has anti-tumor activities. | ||||||||||||||||||||
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References
- [1]. Zhao L, et al. Pharmacological activation of estrogen receptor beta augments innate immunity to suppress cancer metastasis. Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):E3673-E3681. [Content Brief]
- [2]. Sareddy GR, et al. Selective Estrogen Receptor β Agonist LY500307 as a Novel Therapeutic Agent for Glioblastoma. Sci Rep. 2016 Apr 29;6:24185. [Content Brief]
Keywords
