1421854-16-1
1421854-16-1
Chemical Structure
AC-186
- CAS No.: 1421854-16-1
- Formula:C18H17F3O
- Molecular Weight:306.32
IUPAC Name: 4-(4,4-difluoro-1-(2-fluorophenyl)cyclohexyl)phenol
InChIKey: HSMUKSLNDJOZQG-UHFFFAOYSA-N
SMILES: FC1=C(C=CC=C1)C2(C3=CC=C(O)C=C3)CCC(F)(F)CC2
Biological Activity: AC-186 is a selective non-steroidal estrogen receptor β (ERβ) agonist with EC50s of 6 nM and 5000 nM for ERβ and ERα, respectively. AC-186 shows gender selective neuroprotective effects in a male rat model of Parkinson's disease[1].
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AC-186 | 99.61% | AC-186 is a selective non-steroidal estrogen receptor β (ERβ) agonist with EC50s of 6 nM and 5000 nM for ERβ and ERα, respectively. AC-186 shows gender selective neuroprotective effects in a male rat model of Parkinson's disease. | ||||||||||||||||||||
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References
Keywords
