1428-67-7
1428-67-7
Chemical Structure
DPN
Synonym(s): Diarylpropionitrile
- CAS No.: 1428-67-7
- Formula:C15H13NO2
- Molecular Weight:239.27
IUPAC Name: 2,3-bis(4-hydroxyphenyl)propanenitrile
InChIKey: GHZHWDWADLAOIQ-UHFFFAOYSA-N
SMILES: OC1=CC=C(CC(C#N)C2=CC=C(O)C=C2)C=C1
Biological Activity: DPN (Diarylpropionitrile) is a non-steroidal estrogen receptor β (ERβ) selective ligand, with an EC50 of 0.85 nM. DPN has neuroprotective effects in a number of neurological diseases[1][2].
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DPN | 99.66% | DPN (Diarylpropionitrile) is a non-steroidal estrogen receptor β (ERβ) selective ligand, with an EC50 of 0.85 nM. DPN has neuroprotective effects in a number of neurological diseases. | ||||||||||||||||||||
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DPN (Standard) | ≥98% | DPN (Standard) is the analytical standard of DPN. This product is intended for research and analytical applications. DPN (Diarylpropionitrile) is a non-steroidal estrogen receptor β (ERβ) selective ligand, with an EC50 of 0.85 nM. DPN has neuroprotective effects in a number of neurological diseases. | ||||||||||||||||||||
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References
- [1]. Meyers, M. J., et al. Estrogen Receptor-β Potency-Selective Ligands: Structure−Activity Relationship Studies of Diarylpropionitriles and Their Acetylene and Polar Analogues. Journal of Medicinal Chemistry, 2001. 44(24), 4230–4251. [Content Brief]
- [2]. Suwanna N, et al. Neuroprotective effects of diarylpropionitrile against β-amyloid peptide-induced neurotoxicity in rat cultured cortical neurons. Neurosci Lett. 2014 Aug 22;578:44-9. [Content Brief]
