ERα Activator
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(Z)-Ligustilide
0 Images(Z)-Ligustilide is extracted from Ligusticum chuanxiong Hort, has antimicrobial and antifungal activity, exhibits an average antifungal score of 5.6. (Z)-Ligustilide is orally active, it inhibits the expression of FATP5 and DGAT, inhibits fatty acid uptake and esterification in mice and has potential as therapeutics for nonalcoholic fatty liver disease (NAFLD) . (Z)-Ligustilide is also able to reactivate ERα, has epigenetic regulation, and is used in the study of tamoxifen-resistant breast cancer.
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β-Epoxysitosterol
0 ImagesCat. No.: HY-N19469CAS No.: 20835-90-9β-Epoxysitosterol is an Estrogen receptor α agonist. β-Epoxysitosterol accumulates in the plasma, aorta, liver, kidney and heart of hamsters fed with diets containing phytosterol oxidation products. β-Epoxysitosterol can be used in the research of liver cancer.
