β-Epoxysitosterol
β-Epoxysitosterol is an Estrogen receptor α agonist. β-Epoxysitosterol accumulates in the plasma, aorta, liver, kidney and heart of hamsters fed with diets containing phytosterol oxidation products. β-Epoxysitosterol can be used in the research of liver cancer.
For research use only. We do not sell to patients.
- CAS No.: 20835-90-9
- Formula: C29H50O2
- Molecular Weight:430.72
-
Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
ERα |
β-Epoxysitosterol (10 μM) induces luciferase activity, a marker of estrogen receptor α activation, in estrogen receptor α-transfected HeLa cells[1].
β-Epoxysitosterol (120 μM; 24 h) reduces the viability of HepG2 cells to 73%[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:HepG2 cells
-
Concentration:120 μM
-
Incubation Time:24 h
-
Result:Reduced HepG2 cell viability to 73%.
Chemical Information
-
CAS No. 20835-90-9
-
Appearance Solid
-
Molecular Weight 430.72
-
Formula C29H50O2
-
SMILES
C[C@]12[C@]3([C@](O3)(C[C@@]4([C@@]1(CC[C@@]5(C)[C@]4(CC[C@@]5([C@@H](CC[C@H](C(C)C)CC)C)[H])[H])[H])[H])[H])C[C@@H](O)CC2
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
β-Epoxysitosterol Related Classifications
HY-N19469 Related Classifications
Powered by Bioz