1. PROTAC
    Protein Tyrosine Kinase/RTK
  2. SNIPER
    Bcr-Abl
  3. SNIPER(ABL)-019

SNIPER(ABL)-019 

Cat. No.: HY-111873
Handling Instructions

SNIPER(ABL)-019, conjugating Dasatinib (ABL inhibitor) to MV-1 (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 0.3 μM.

For research use only. We do not sell to patients.

SNIPER(ABL)-019 Chemical Structure

SNIPER(ABL)-019 Chemical Structure

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Description

SNIPER(ABL)-019, conjugating Dasatinib (ABL inhibitor) to MV-1 (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 0.3 μM[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

1177.85

Formula

C₆₀H₇₇ClN₁₂O₉S

SMILES

CC1=C(NC(C2=CN=C(NC3=CC(N4CCN(C(COCCOCCOCCNC([[email protected]](C(C5=CC=CC=C5)C6=CC=CC=C6)NC([[email protected]]7N(C([[email protected]@H](NC([[email protected]](C)NC)=O)C8CCCCC8)=O)CCC7)=O)=O)=O)CC4)=NC(C)=N3)S2)=O)C(Cl)=CC=C1

Shipping

Room temperature in continental US; may vary elsewhere

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C1   V1   C2   V2

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Product Name:
SNIPER(ABL)-019
Cat. No.:
HY-111873
Quantity:

SNIPER(ABL)-019

Cat. No.: HY-111873