1. PROTAC
  2. Target Protein Ligand-Linker Conjugate
  3. Dual PARP EGFR ligand for PROTAC

Dual PARP EGFR ligand for PROTAC 

Cat. No.: HY-141486
Handling Instructions

Dual PARP EGFR ligand for PROTAC incorporates a ligand for PARP and EGFR , and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). Dual PARP EGFR ligand for PROTAC can be used in the synthesis of DP-C-4, which is CRBN-based dual PROTAC for simultaneous degradation of EGFR and PARP.

For research use only. We do not sell to patients.

Dual PARP EGFR ligand for PROTAC Chemical Structure

Dual PARP EGFR ligand for PROTAC Chemical Structure

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Description

Dual PARP EGFR ligand for PROTAC incorporates a ligand for PARP and EGFR , and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). Dual PARP EGFR ligand for PROTAC can be used in the synthesis of DP-C-4, which is CRBN-based dual PROTAC for simultaneous degradation of EGFR and PARP[1].

Molecular Weight

1020.52

Formula

C₅₃H₅₆ClF₂N₉O₈

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
Dual PARP EGFR ligand for PROTAC
Cat. No.:
HY-141486
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