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Cat. No.: HY-128817

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cIAP1 Ligand-Linker Conjugates 12

Name: cIAP1 Ligand-Linker Conjugates 12
Brand: MedChemExpress
SKU: HY-128817
Availability: PreOrder

(Synonyms: E3 ligase Ligand-Linker Conjugates 38)

cIAP1 Ligand-Linker Conjugates 12 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 12 can be used to design SNIPERs.

For research use only. We do not sell to patients.

CAS No.: 2095244-52-1
Formula: C₄₆H₆₄N₄O₁₂S₂
Molecular Weight:929.15

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

cIAP1 Ligand-Linker Conjugates 12 Chemical Structure

CAS No.: 2095244-52-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Chemical Information
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Description

cIAP1 Ligand-Linker Conjugates 12 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 12 can be used to design SNIPERs^[1].

IC₅₀ & Target

cIAP1

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

CAS No. 2095244-52-1
Molecular Weight 929.15
Formula C₄₆H₆₄N₄O₁₂S₂
SMILES

C[C@H](N(C(OC(C)(C)C)=O)C)C(N[C@@H](C1CCCCC1)C(N(CCC2)[C@@H]2C3=NC(C(C4=CC=CC(OCCOCCOCCOCCOS(C5=CC=C(C)C=C5)(=O)=O)=C4)=O)=CS3)=O)=O
Synonyms

E3 ligase Ligand-Linker Conjugates 38
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ohoka N, et al. In Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs). J Biol Chem. 2017 Mar 17;292(11):4556-4570. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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cIAP1 Ligand-Linker Conjugates 12

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