1. PROTAC
    Protein Tyrosine Kinase/RTK
  2. SNIPER
    Bcr-Abl
  3. SNIPER(ABL)-058

SNIPER(ABL)-058 

Cat. No.: HY-111859
Handling Instructions

SNIPER(ABL)-058, conjugating Imatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 μM.

For research use only. We do not sell to patients.

SNIPER(ABL)-058 Chemical Structure

SNIPER(ABL)-058 Chemical Structure

CAS No. : 2222354-61-0

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Description

SNIPER(ABL)-058, conjugating Imatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 μM[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

1150.39

Formula

C₆₂H₇₅N₁₁O₉S

CAS No.

2222354-61-0

SMILES

CC1=CC=C(NC(C2=CC=C(CN3CCN(C(COCCOCCOCCOC4=CC(C(C5=CSC([[email protected]]6N(C([[email protected]](C7CCCCC7)NC([[email protected]](C)NC)=O)=O)CCC6)=N5)=O)=CC=C4)=O)CC3)C=C2)=O)C=C1NC8=NC=CC(C9=CC=CN=C9)=N8

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Room temperature in continental US; may vary elsewhere

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Product Name:
SNIPER(ABL)-058
Cat. No.:
HY-111859
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SNIPER(ABL)-058

Cat. No.: HY-111859