FAK ligand-Linker Conjugate 1
Based on 1 Customer Validation
FAK ligand-Linker Conjugate 1 incorporates a ligand for FAK, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). FAK ligand-Linker Conjugate 1 can be extensively used for PROTAC-mediated protein degradation.
For research use only. We do not sell to patients.
- Purity: 99.29%
- CAS No.: 2307461-45-4
- Formula: C25H28F3N5O6S
- Molecular Weight:583.58
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2307461-45-4
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Appearance Solid
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Molecular Weight 583.58
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Formula C25H28F3N5O6S
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Color White to off-white
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SMILES
O=C(O)CCOCCOC1=CC=C(NC2=NC=C(C(F)(F)F)C(NCC3=CC=CC(N(C)S(=O)(C)=O)=C3)=N2)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : 100 mg/mL (171.36 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7136 mL | 8.5678 mL | 17.1356 mL | 42.8390 mL |
| 5 mM | 0.3427 mL | 1.7136 mL | 3.4271 mL | 8.5678 mL | |
| 10 mM | 0.1714 mL | 0.8568 mL | 1.7136 mL | 4.2839 mL | |
| 15 mM | 0.1142 mL | 0.5712 mL | 1.1424 mL | 2.8559 mL | |
| 20 mM | 0.0857 mL | 0.4284 mL | 0.8568 mL | 2.1420 mL | |
| 25 mM | 0.0685 mL | 0.3427 mL | 0.6854 mL | 1.7136 mL | |
| 30 mM | 0.0571 mL | 0.2856 mL | 0.5712 mL | 1.4280 mL | |
| 40 mM | 0.0428 mL | 0.2142 mL | 0.4284 mL | 1.0710 mL | |
| 50 mM | 0.0343 mL | 0.1714 mL | 0.3427 mL | 0.8568 mL | |
| 60 mM | 0.0286 mL | 0.1428 mL | 0.2856 mL | 0.7140 mL | |
| 80 mM | 0.0214 mL | 0.1071 mL | 0.2142 mL | 0.5355 mL | |
| 100 mM | 0.0171 mL | 0.0857 mL | 0.1714 mL | 0.4284 mL |
FAK ligand-Linker Conjugate 1 Related Classifications
HY-44148 Related Classifications
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