A 410099.1, amine-Boc hydrochloride
Based on 1 Customer Validation
A 410099.1, amine-Boc hydrochloride is a functionalized IAP ligand and can be used for the synthesis of PROTACs, such as PROTACs targeting BTK (PROTACs 4 and 5).
For research use only. We do not sell to patients.
- Purity: 99.71%
- CAS No.: 2374122-37-7
- Formula: C32H50ClN5O5
- Molecular Weight:620.22
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
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cIAP1 |
Chemical Information
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CAS No. 2374122-37-7
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Appearance Solid
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Molecular Weight 620.22
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Formula C32H50ClN5O5
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Color White to off-white
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SMILES
O=C(N(C[C@H]1N)[C@@H](C1)C(N[C@H]2C3=CC=CC=C3CCC2)=O)[C@H](C4CCCCC4)NC([C@H](C)N(C)C(OC(C)(C)C)=O)=O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (161.23 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6123 mL | 8.0617 mL | 16.1233 mL | 40.3083 mL |
| 5 mM | 0.3225 mL | 1.6123 mL | 3.2247 mL | 8.0617 mL | |
| 10 mM | 0.1612 mL | 0.8062 mL | 1.6123 mL | 4.0308 mL | |
| 15 mM | 0.1075 mL | 0.5374 mL | 1.0749 mL | 2.6872 mL | |
| 20 mM | 0.0806 mL | 0.4031 mL | 0.8062 mL | 2.0154 mL | |
| 25 mM | 0.0645 mL | 0.3225 mL | 0.6449 mL | 1.6123 mL | |
| 30 mM | 0.0537 mL | 0.2687 mL | 0.5374 mL | 1.3436 mL | |
| 40 mM | 0.0403 mL | 0.2015 mL | 0.4031 mL | 1.0077 mL | |
| 50 mM | 0.0322 mL | 0.1612 mL | 0.3225 mL | 0.8062 mL | |
| 60 mM | 0.0269 mL | 0.1344 mL | 0.2687 mL | 0.6718 mL | |
| 80 mM | 0.0202 mL | 0.1008 mL | 0.2015 mL | 0.5039 mL | |
| 100 mM | 0.0161 mL | 0.0806 mL | 0.1612 mL | 0.4031 mL |