2. Signaling Pathways
  3. PROTAC
  4. Ligands for E3 Ligase
  5. IAP Isoform

IAP

 

IAP Related Products (9):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-128808
    cIAP1 ligand 1 2095244-42-9 99.07%
    cIAP1 ligand 1 is the LCL161 derivative based IAP ligand. cIAP1 ligand 1 can be connected to the ABL ligand for protein by a linker to form SNIPER.
    cIAP1 ligand 1
  • HY-139999
    LCL-PEG3-N3
    LCL-PEG3-N3 is a decoy oligonucleotide ligand for E3 ligase which can be used for developing chimeric molecules LCL-ER(dec), degrading the estrogen receptor. LCL-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
    LCL-PEG3-N3
  • HY-130842
    β-Naphthoflavone-CH2-Br 1282513-77-2
    β-Naphthoflavone-CH2-Br (β-NF-CH2-Br) is an arylhydrocarbon receptor (AhR) ligand. β-Naphthoflavone-CH2-Br can be used to synthesize the PROTAC β-NF-JQ1(HY-130256).
    β-Naphthoflavone-CH2-Br
  • HY-111850
    Bestatin-amido-Me 339186-54-8
    Bestatin-amido-Me, the Bestatin-based IAP ligand, binds to ABL inhibitor via a linker to form SNIPER.
    Bestatin-amido-Me
  • HY-111853
    MV-1-NH-Me 2095244-62-3
    MV-1-NH-Me, the MV-1 based IAP ligand, binds to ABL inhibitor via a linker to form SNIPER.
    MV-1-NH-Me
  • HY-139999A
    LCL-PEG3-N3 hydrochloride
    LCL-PEG3-N3 (hydrochloride) is a decoy oligonucleotide ligand for E3 ligase which can be used for developing chimeric molecules LCL-ER(dec), degrading the estrogen receptor. LCL-PEG3-N3 (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
    LCL-PEG3-N3 hydrochloride
  • HY-130269
    β-Naphthoflavone-CH2-OH 2752755-32-9
    β-Naphthoflavone-CH2-OH (β-NF-CH2-OH) is a ligand for arylhydrocarbon receptor (AhR) E3 ligase. β-Naphthoflavone-CH2-OH can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs (e.g., β-naphthoflavone-JQ1) that recruit the AhR E3 ligase complex by incorporating AhR ligands into chimeric molecules. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins .
    β-Naphthoflavone-CH2-OH
  • HY-131189
    N-Boc-SBP-0636457-OH
    N-Boc-SBP-0636457-OH, a ligand for E3 ubiquitin ligase, is used in the recruitment of IAP E3 ligases. N-Boc-SBP-0636457-OH can be connected to the ligand for Bcl-xL by a linker to form PROTAC Bcl-xL degrader-1 (HY-131188).
    N-Boc-SBP-0636457-OH
  • HY-128809
    cIAP1 ligand 2 2357114-70-4
    cIAP1 ligand 2 is the LCL161 derivative based IAP ligand. cIAP1 ligand 2 can be connected to the ABL ligand for protein by a linker to form SNIPER.
    cIAP1 ligand 2