1. PROTAC
  2. Ligand for E3 Ligase
  3. N-Boc-SBP-0636457-OH

N-Boc-SBP-0636457-OH 

Cat. No.: HY-131189
Handling Instructions

N-Boc-SBP-0636457-OH, a ligand for E3 ubiquitin ligase, is used in the recruitment of IAP E3 ligases. N-Boc-SBP-0636457-OH can be connected to the ligand for Bcl-xL by a linker to form PROTAC Bcl-xL degrader-1 (HY-131188).

For research use only. We do not sell to patients.

N-Boc-SBP-0636457-OH Chemical Structure

N-Boc-SBP-0636457-OH Chemical Structure

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Description

N-Boc-SBP-0636457-OH, a ligand for E3 ubiquitin ligase, is used in the recruitment of IAP E3 ligases. N-Boc-SBP-0636457-OH can be connected to the ligand for Bcl-xL by a linker to form PROTAC Bcl-xL degrader-1 (HY-131188).

IC50 & Target[1]

cIAP1

 

Molecular Weight

572.69

Formula

C₃₀H₄₄N₄O₇

SMILES

O=C(N[[email protected]@H]1CCCC2=C1C=CC(O)=C2)[[email protected]@H]3C(C)(C[[email protected]@]([H])(N3C4=O)OCC[[email protected]@H]4NC([[email protected]@H](N(C)C(OC(C)(C)C)=O)C)=O)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

N-Boc-SBP-0636457-OHLigand for E3 LigaseE3 ligase-recruiting MoietycancerMOLT-4MyLa1929degradermultipleInhibitorinhibitorinhibit

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Product name:
N-Boc-SBP-0636457-OH
Cat. No.:
HY-131189
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