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  4. (7R)-SBP-0636457

(7R)-SBP-0636457  (Synonyms: (7R)-SBI-0636457; (7R)-SB1-0636457)

Cat. No.: HY-125378A Purity: 98.36%
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(7R)-SBP-0636457 is the isomer of SBP-0636457 (HY-125378), and can be used as an experimental control. SBP-0636457 (SB1-0636457) is a SMAC mimetic, and as an IAP antagonist. SBP-0636457 binds to the BIR-domains of the IAP proteins, with a Ki of 0.27 μM. SBP-0636457 can be used for the research of solid tumors and hematologic cancers.

For research use only. We do not sell to patients.

(7R)-SBP-0636457 Chemical Structure

(7R)-SBP-0636457 Chemical Structure

CAS No. : 1422180-61-7

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Based on 1 publication(s) in Google Scholar

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Description

(7R)-SBP-0636457 is the isomer of SBP-0636457 (HY-125378), and can be used as an experimental control. SBP-0636457 (SB1-0636457) is a SMAC mimetic, and as an IAP antagonist. SBP-0636457 binds to the BIR-domains of the IAP proteins, with a Ki of 0.27 μM. SBP-0636457 can be used for the research of solid tumors and hematologic cancers[1][2].

Molecular Weight

456.58

Formula

C25H36N4O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C([C@H]1C(C)(C)C[C@](N21)([H])OCC[C@H](NC([C@@H](NC)C)=O)C2=O)N[C@@H]3CCCC4=C3C=CC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Purity & Documentation
References
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(7R)-SBP-0636457 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(7R)-SBP-06364571422180-61-7(7R)-SBI-0636457 (7R)-SB1-0636457OthersSMACmimeticIAPBIR-domainstumourshematologiccancersInhibitorinhibitorinhibit

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