1. Signaling Pathways
  2. Apoptosis
  3. IAP
  4. IAP Inhibitors

IAP Inhibitors

cIAP

cIAP-1

cIAP-2

XIAP

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

IAP Degraders, Inhibitors & Antagonists
Product Name cIAP cIAP-1 cIAP-2 XIAP Purity
SM-164  
cIAP-1, Ki: 0.31 nM
cIAP-2, Ki: 1.1 nM
  99.65%
AZD5582  
cIAP1, IC50: 15 nM
cIAP2, IC50: 21 nM
XIAP, IC50: 15 nM
98.21%
Xevinapant  
cIAP1, Ki: 1.9 nM
cIAP2, Ki: 5.1 nM
XIAP, Ki: 66.4 nM
99.94%
Embelin      
XIAP, IC50: 4.1 μM
98.75%
Xevinapant hydrochloride  
cIAP1, Ki: 1.9 nM
cIAP2, Ki: 5.1 nM
XIAP, Ki: 66.4 nM
98.80%
SM-164 Hydrochloride  
cIAP-1, Ki: 0.31 nM
cIAP-2, Ki: 1.1 nM
  98.10%
AZD5582 dihydrochloride  
cIAP1, IC50: 15 nM
cIAP2, IC50: 21 nM
XIAP, IC50: 15 nM
98.67%
TD1092  
cIAP1
cIAP2
XIAP
99.49%
SBP-0636457      
XIAP, Ki: 0.27 μM
98.42%
LSD1-IN-26  
cIAP-1
   
XIAP/cIAP1 antagonist-1  
cIAP1, IC50: 0.32 nM
 
XIAP, IC50: 5.1 nM
T-3256336  
cIAP1, IC50: 1.3 nM
 
XIAP, IC50: 200 nM