HG-7-85-01-NH2
Based on 1 Customer Validation
HG-7-85-01-NH2 is the HG-7-85-01 (ABL inhibitor) based moiety, binds to IAP ligand via a linker to form SNIPER.
For research use only. We do not sell to patients.
- Purity: 98.05%
- CAS No.: 1258391-29-5
- Formula: C27H27F3N6OS
- Molecular Weight:540.60
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BaF3 | EC50 |
>10 μM
Compound: 20
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Cytotoxicity against mouse BA/F3 cells expressing imatinib resistant Bcr-Abl T3151 mutant
Cytotoxicity against mouse BA/F3 cells expressing imatinib resistant Bcr-Abl T3151 mutant
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[PMID: 22819762] |
| BaF3 | EC50 |
>10 μM
Compound: 20
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Cytotoxicity against mouse BA/F3 cells expressing wild type Bcr-Abl
Cytotoxicity against mouse BA/F3 cells expressing wild type Bcr-Abl
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[PMID: 22819762] |
| BaF3 | EC50 |
>10 μM
Compound: 20
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Cytotoxicity against wild type mouse BA/F3 cells
Cytotoxicity against wild type mouse BA/F3 cells
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[PMID: 22819762] |
Chemical Information
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CAS No. 1258391-29-5
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Appearance Solid
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Molecular Weight 540.60
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Formula C27H27F3N6OS
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Color Off-white to light yellow
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SMILES
O=C(NC1=CC=C(CN2CCN(CC)CC2)C(C(F)(F)F)=C1)C3=CC=CC(C4=CC=C5C(SC(N)=N5)=N4)=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (231.22 mM; ultrasonic and adjust pH to 5 with H2O; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8498 mL | 9.2490 mL | 18.4980 mL | 46.2449 mL |
| 5 mM | 0.3700 mL | 1.8498 mL | 3.6996 mL | 9.2490 mL | |
| 10 mM | 0.1850 mL | 0.9249 mL | 1.8498 mL | 4.6245 mL | |
| 15 mM | 0.1233 mL | 0.6166 mL | 1.2332 mL | 3.0830 mL | |
| 20 mM | 0.0925 mL | 0.4624 mL | 0.9249 mL | 2.3122 mL | |
| 25 mM | 0.0740 mL | 0.3700 mL | 0.7399 mL | 1.8498 mL | |
| 30 mM | 0.0617 mL | 0.3083 mL | 0.6166 mL | 1.5415 mL | |
| 40 mM | 0.0462 mL | 0.2312 mL | 0.4624 mL | 1.1561 mL | |
| 50 mM | 0.0370 mL | 0.1850 mL | 0.3700 mL | 0.9249 mL | |
| 60 mM | 0.0308 mL | 0.1541 mL | 0.3083 mL | 0.7707 mL | |
| 80 mM | 0.0231 mL | 0.1156 mL | 0.2312 mL | 0.5781 mL | |
| 100 mM | 0.0185 mL | 0.0925 mL | 0.1850 mL | 0.4624 mL |
HG-7-85-01-NH2 Related Classifications
HY-131178 Related Classifications
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