1. PROTAC
    Protein Tyrosine Kinase/RTK
  2. SNIPER
    Bcr-Abl
  3. SNIPER(ABL)-024

SNIPER(ABL)-024 

Cat. No.: HY-111861
Handling Instructions

SNIPER(ABL)-024, conjugating GNF5 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 5μM.

For research use only. We do not sell to patients.

SNIPER(ABL)-024 Chemical Structure

SNIPER(ABL)-024 Chemical Structure

CAS No. : 2222355-77-1

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Description

SNIPER(ABL)-024, conjugating GNF5 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 5μM[1].

References
Molecular Weight

1031.15

Formula

C₅₂H₆₁F₃N₈O₉S

CAS No.

2222355-77-1

SMILES

O=C(NCCOCCOCCOCCOC1=CC(C(C2=CSC([[email protected]]3N(C([[email protected]](C4CCCCC4)NC([[email protected]](C)NC)=O)=O)CCC3)=N2)=O)=CC=C1)C5=CC=CC(C6=NC=NC(NC7=CC=C(OC(F)(F)F)C=C7)=C6)=C5

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
SNIPER(ABL)-024
Cat. No.:
HY-111861
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SNIPER(ABL)-024

Cat. No.: HY-111861