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Cat. No.: HY-128820

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cIAP1 Ligand-Linker Conjugates 1

Name: cIAP1 Ligand-Linker Conjugates 1
Brand: MedChemExpress
SKU: HY-128820
Availability: PreOrder

(Synonyms: E3 ligase Ligand-Linker Conjugates 41)

cIAP1 Ligand-Linker Conjugates 1 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 1 can be used to design SNIPERs.

For research use only. We do not sell to patients.

CAS No.: 2357114-75-9
Formula: C₄₂H₅₇N₅O₉S
Molecular Weight:808.00

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

cIAP1 Ligand-Linker Conjugates 1 Chemical Structure

CAS No.: 2357114-75-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Chemical Information
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Description

cIAP1 Ligand-Linker Conjugates 1 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 1 can be used to design SNIPERs^[1].

IC₅₀ & Target

cIAP1

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

CAS No. 2357114-75-9
Molecular Weight 808.00
Formula C₄₂H₅₇N₅O₉S
SMILES

O=C(OCC1=CC=CC=C1)N(C)[C@@H](C)C(N[C@@H](C2CCCCC2)C(N3[C@H](C4=NC(C(C5=CC(OCCOCCOCCOCCN)=CC=C5)=O)=CS4)CCC3)=O)=O
Synonyms

E3 ligase Ligand-Linker Conjugates 41
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Purity & Documentation
References

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