1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugate
  3. Pomalidomide-PEG4-C-COOH

Pomalidomide-PEG4-C-COOH (Synonyms: Cereblon Ligand -Linker Conjugates 1; E3 Ligase Ligand-Linker Conjugates 1)

Cat. No.: HY-21930 Purity: 99.10%
Handling Instructions

Pomalidomide-PEG4-C-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.

For research use only. We do not sell to patients.

Pomalidomide-PEG4-C-COOH Chemical Structure

Pomalidomide-PEG4-C-COOH Chemical Structure

CAS No. : 2097938-44-6

Size Price Stock Quantity
100 mg USD 550 In-stock
Estimated Time of Arrival: December 31
500 mg USD 1950 In-stock
Estimated Time of Arrival: December 31
1 g USD 3350 In-stock
Estimated Time of Arrival: December 31
2 g USD 4900 Get quote
5 g   Get quote  
10 g   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Pomalidomide-PEG4-C-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.

IC50 & Target

Cereblon

 

Molecular Weight

507.49

Formula

C₂₃H₂₉N₃O₁₀

CAS No.
SMILES

O=C(N(C(CCC1=O)C(N1)=O)C2=O)C(C2=CC=C3)=C3NCCOCCOCCOCCOCC(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (98.52 mM; Need ultrasonic)

Ethanol : 25 mg/mL (49.26 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9705 mL 9.8524 mL 19.7048 mL
5 mM 0.3941 mL 1.9705 mL 3.9410 mL
10 mM 0.1970 mL 0.9852 mL 1.9705 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: 99.10%

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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Keywords:

Pomalidomide-PEG4-C-COOHCereblon Ligand -Linker Conjugates 1 E3 Ligase Ligand-Linker Conjugates 1E3 Ligase Ligand-Linker ConjugateInhibitorinhibitorinhibit

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Product Name:
Pomalidomide-PEG4-C-COOH
Cat. No.:
HY-21930
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