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Cat. No.: HY-128818

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cIAP1 Ligand-Linker Conjugates 5

Name: cIAP1 Ligand-Linker Conjugates 5
Brand: MedChemExpress
SKU: HY-128818
Availability: PreOrder

(Synonyms: E3 ligase Ligand-Linker Conjugates 39)

cIAP1 Ligand-Linker Conjugates 5 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 5 can be used to design SNIPERs.

For research use only. We do not sell to patients.

CAS No.: 2113688-20-1
Formula: C₃₇H₅₅N₅O₈S
Molecular Weight:729.93

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

cIAP1 Ligand-Linker Conjugates 5 Chemical Structure

CAS No.: 2113688-20-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- Description
- IC₅₀ & Target
Chemical Information
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Biological Activity

Description

cIAP1 Ligand-Linker Conjugates 5 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 5 can be used to design SNIPERs^[1].

IC₅₀ & Target

cIAP1

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

CAS No. 2113688-20-1
Molecular Weight 729.93
Formula C₃₇H₅₅N₅O₈S
SMILES

C[C@H](N(C(OC(C)(C)C)=O)C)C(N[C@@H](C1CCCCC1)C(N(CCC2)[C@@H]2C3=NC(C(C4=CC=CC(OCCOCCOCCN)=C4)=O)=CS3)=O)=O
Synonyms

E3 ligase Ligand-Linker Conjugates 39
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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