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K-Ras ligand-Linker Conjugate 4

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K-Ras ligand-Linker Conjugate 4 incorporates a ligand for K-Ras recruiting moiety, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 4 can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells.

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  • Purity: 98.76%
  • CAS No.: 2378261-83-5
  • Formula: C35H51N7O8
  • Molecular Weight:697.82
  • Storage:

    -20°C, stored under nitrogen

    * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

  • K-Ras ligand-Linker Conjugate 4 Chemical Structure
    K-Ras ligand-Linker Conjugate 4 Chemical Structure
CAS No.: 2378261-83-5
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609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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  • K-Ras ligand-Linker Conjugate 4 Chemical Structure
    K-Ras ligand-Linker Conjugate 4 Chemical Structure
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  • K-Ras ligand-Linker Conjugate 4