1. Signaling Pathways
  2. GPCR/G Protein
  3. Ras
  4. K-Ras Inhibitors

K-Ras Inhibitors

K-Ras

H-Ras

Ras

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Sorry. There is currently no product that acts on isoform K-Ras together.

Please try each isoform separately.

K-Ras Specific Inhibitors & Antagonists
Product Name K-Ras K-Ras Selectivity Purity
Sotorasib
KRAS(G12C)
Selective Inhibitor 99.72%
Adagrasib
KRas G12C
Selective Inhibitor 99.72%
BI-2852
KRAS(G12C), IC50: 450 nM
KRAS(G12C), Kd: 750 nM
Selective Inhibitor 98.74%
BI-3406
KRAS-SOS1, IC50: 6 nM
Selective Inhibitor 99.79%
MRTX1133
KRas G12D, Kd: 0.2 pM
Selective Inhibitor 99.25%
MRTX1133 formic
KRas G12D, Kd: 0.2 pM
Selective Inhibitor 98.23%
BAY-293
KRAS-SOS1, IC50: 21 nM
Selective Inhibitor 98.06%
ARS-1620
KRAS(G12C)
Selective Inhibitor 99.20%
PROTAC K-Ras Degrader-1
KRAS(G12C)
Selective Inhibitor 98.06%
LC-2
KRAS(G12C), DC50: 0.25-0.76 μM
Selective Inhibitor ≥95.0%
MRTX-1257
KRAS(G12C)
Selective Inhibitor 98.62%
Sotorasib racemate
KRas G12C
Selective Inhibitor 98.99%
ARS-853
KRAS(G12C), IC50: 2.5 μM
Selective Inhibitor 98.39%
ARS-1323-alkyne
KRAS(G12C)
Selective Inhibitor 99.56%
ARS-1323
KRas G12C
Selective Inhibitor ≥98.0%
ARS-1630
KRAS(G12C)
Selective Inhibitor 98.01%
K-Ras G12C-IN-2
KRas G12C
Selective Inhibitor ≥98.0%
ASP2453
KRas G12C, IC50: 40 nM
Selective Inhibitor
JDQ-443
KRas G12C
Selective Inhibitor
KRAS inhibitor-6
KRAS(G12C)
Selective Inhibitor
KRAS inhibitor-8
KRAS(G12C)
Selective Inhibitor
KRAS inhibitor-7
KRAS(G12C)
Selective Inhibitor
KRAS G12C inhibitor 15
KRas G12C, IC50: 5 nM
Selective Inhibitor
KRAS G12C inhibitor 5
KRas G12C
Selective Inhibitor
KRAS G12C inhibitor 18
KRas G12C
Selective Inhibitor
KRAS G12C inhibitor 13
KRas G12C
Selective Inhibitor
KRAS G12C inhibitor 17
KRas G12C, IC50: 5 nM
Selective Inhibitor
KRAS G12C inhibitor 16
KRas G12C, IC50: 97 nM
Selective Inhibitor
KRAS G12C inhibitor 14
KRas G12C, IC50: 18 nM
Selective Inhibitor
KRas G12C inhibitor 4
KRas G12C
Selective Inhibitor
KRas G12C inhibitor 1
KRas G12C
Selective Inhibitor
MRTX849 acid
KRas G12C
Selective Inhibitor
MRTX849 ethoxypropanoic acid
KRas G12C
Selective Antagonist
KRas G12C inhibitor 3
KRas G12C
Selective Inhibitor
KRAS G12D inhibitor 7
KRas G12D
Selective Inhibitor
KRas G12C inhibitor 2
KRas G12C
Selective Inhibitor
6H05
K-Ras(G12C)
Selective Inhibitor
SAH-SOS1A TFA
KRas G12C, EC50: 140 nM
KRas G12D, EC50: 109 nM
KRas G12V, EC50: 154 nM
KRas G12S, EC50: 155 nM
KRas Q61H, EC50: 175 nM
K-Ras WT, EC50: 106 nM
Pan Inhibitor 99.00%
KRAS inhibitor-10
KRas G12C
Pan Inhibitor 99.86%
SAH-SOS1A
KRas G12C, EC50: 140 nM
KRas G12D, EC50: 109 nM
KRas G12V, EC50: 154 nM
KRas G12S, EC50: 155 nM
KRas Q61H, EC50: 175 nM
K-Ras WT, EC50: 106 nM
Pan Inhibitor
RM-018
KRAS (G12C)
KRAS (G12C/Y96D)
Inhibitor
Atrovastatin-PEG3-FITC
KRAS-PDEδ
Inhibitor