1. GPCR/G Protein
  2. Ras

MRTX-1257 

Cat. No.: HY-114436
Handling Instructions

MRTX-1257 is an irreversible covalent inhibitor of KRAS G12C with antitumor efficacy.

For research use only. We do not sell to patients.

MRTX-1257 Chemical Structure

MRTX-1257 Chemical Structure

CAS No. : 2206736-04-9

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

MRTX-1257 is an irreversible covalent inhibitor of KRAS G12C with antitumor efficacy.

IC50 & Target

KRAS G12C[1]

References
Molecular Weight

565.71

Formula

C₃₃H₃₉N₇O₂

CAS No.

2206736-04-9

SMILES

N#CC[[email protected]@H]1N(C(C=C)=O)CCN(C2=C3C(CN(C4=C5C(C)=CC=CC5=CC=C4)CC3)=NC(OC[[email protected]]6N(C)CCC6)=N2)C1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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MRTX-1257
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HY-114436
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MRTX-1257

Cat. No.: HY-114436