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  3. AMG-510 racemate

AMG-510 racemate 

Cat. No.: HY-114277A Purity: 98.99%
Handling Instructions

AMG-510 racemate is the racemate of AMG-510. AMG-510 is a potent, orally bioavailable, and selective KRAS G12C covalent inhibitor with anti-tumor activity.

For research use only. We do not sell to patients.

AMG-510 racemate Chemical Structure

AMG-510 racemate Chemical Structure

CAS No. : 2252403-56-6

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
5 mg USD 130 In-stock
Estimated Time of Arrival: December 31
10 mg USD 200 In-stock
Estimated Time of Arrival: December 31
50 mg USD 550 In-stock
Estimated Time of Arrival: December 31
100 mg USD 940 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

AMG-510 racemate is the racemate of AMG-510. AMG-510 is a potent, orally bioavailable, and selective KRAS G12C covalent inhibitor with anti-tumor activity.

IC50 & Target[1]

KRas G12C

 

Molecular Weight

560.59

Formula

C₃₀H₃₀F₂N₆O₃

CAS No.

2252403-56-6

SMILES

O=C1N(C2=C(C)C=CN=C2C(C)C)C3=NC(C4=C(O)C=CC=C4F)=C(F)C=C3C(N5[[email protected]@H](C)CN(C(C=C)=O)CC5)=N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility
In Vitro: 

DMSO : 3.85 mg/mL (6.87 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7838 mL 8.9192 mL 17.8383 mL
5 mM 0.3568 mL 1.7838 mL 3.5677 mL
10 mM --- --- ---
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: 98.99%

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Keywords:

AMG-510AMG510AMG 510RasInhibitorinhibitorinhibit

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Product Name:
AMG-510 racemate
Cat. No.:
HY-114277A
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