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BAY-293 

Cat. No.: HY-114398
Handling Instructions

BAY-293 is a potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction with an IC50 of 21 nM.

For research use only. We do not sell to patients.

BAY-293 Chemical Structure

BAY-293 Chemical Structure

CAS No. : 2244904-70-7

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

BAY-293 is a potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction with an IC50 of 21 nM[1].

IC50 & Target

IC50: 21 nM (KRAS-SOS1 interaction)[1]

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2293 mL 11.1463 mL 22.2926 mL
5 mM 0.4459 mL 2.2293 mL 4.4585 mL
10 mM 0.2229 mL 1.1146 mL 2.2293 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

448.58

Formula

C₂₅H₂₈N₄O₂S

CAS No.

2244904-70-7

SMILES

COC1=C(OC)C=C(N=C(C)N=C2N[[email protected]](C)C3=CC(C4=C(CNC)C=CC=C4)=CS3)C2=C1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
BAY-293
Cat. No.:
HY-114398
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BAY-293

Cat. No.: HY-114398