2. GPCR/G Protein MAPK/ERK Pathway
  3. Ras SOS1
  4. (S)-BAY-293

(S)-BAY-293 is a negative control of BAY 293. BAY 293 is a potent KRAS-SOS1 interaction inhibitor.

For research use only. We do not sell to patients.

(S)-BAY-293

(S)-BAY-293 Chemical Structure

CAS No. : 2244904-69-4

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Other Forms of (S)-BAY-293:

(S)-BAY-293 Related Antibodies

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Description

(S)-BAY-293 is a negative control of BAY 293. BAY 293 is a potent KRAS-SOS1 interaction inhibitor[1].

Cellular Effect
Cell Line Type Value Description References
Calu-1 IC50
1840 1
Compound: Compound 24
Antiproliferative activity against human Calu-1 cells assessed as inhibition of cell viability incubated for 72 hrs by Cell Titer Glo assay
Antiproliferative activity against human Calu-1 cells assessed as inhibition of cell viability incubated for 72 hrs by Cell Titer Glo assay
[PMID: 30683722]
K562 IC50
7500 1
Compound: Compound 24
Antiproliferative activity against human K562 cells assessed as inhibition of cell viability incubated for 72 hrs by Cell Titer Glo assay
Antiproliferative activity against human K562 cells assessed as inhibition of cell viability incubated for 72 hrs by Cell Titer Glo assay
[PMID: 30683722]
MOLM-13 IC50
7570 1
Compound: Compound 24
Antiproliferative activity against human MOLM-13 cells assessed as inhibition of cell viability incubated for 72 hrs by Cell Titer Glo assay
Antiproliferative activity against human MOLM-13 cells assessed as inhibition of cell viability incubated for 72 hrs by Cell Titer Glo assay
[PMID: 30683722]
NCI-H358 IC50
3390 1
Compound: Compound 24
Antiproliferative activity against human NCI-H358 cells assessed as inhibition of cell viability incubated for 72 hrs by Cell Titer Glo assay
Antiproliferative activity against human NCI-H358 cells assessed as inhibition of cell viability incubated for 72 hrs by Cell Titer Glo assay
[PMID: 30683722]
Molecular Weight

448.58

Formula

C25H28N4O2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

COC1=C(OC)C=C(N=C(C)N=C2N[C@@H](C)C3=CC(C4=C(CNC)C=CC=C4)=CS3)C2=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 97.8%

SDS (251 KB)

COA (252 KB)

Handling Instructions (2659 KB)
References
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(S)-BAY-293 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S)-BAY-2932244904-69-4RasSOS1Ras/Rac guanine nucleotide exchange factor 1Inhibitorinhibitorinhibit

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HY-114398A
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