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  3. MRTX1133

MRTX1133 

Cat. No.: HY-134813
Handling Instructions

MRTX1133 is a highly selective, first-in-class inhibitor of KRAS G12D. MRTX1133 targets the KRAS G12D protein in both active and inactive states. MRTX1133 selectively inhibits KRAS G12D mutant, but not KRAS wild-type, tumor cells.

For research use only. We do not sell to patients.

MRTX1133 Chemical Structure

MRTX1133 Chemical Structure

CAS No. : 2621928-55-8

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Description

MRTX1133 is a highly selective, first-in-class inhibitor of KRAS G12D. MRTX1133 targets the KRAS G12D protein in both active and inactive states. MRTX1133 selectively inhibits KRAS G12D mutant, but not KRAS wild-type, tumor cells[1][2].

IC50 & Target

KRas G12D

 

In Vivo

MRTX1133 demonstrates dose-dependent inhibition of the KRAS pathway tumor regression in G12D mutant tumor models[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

600.63

Formula

C₃₃H₃₁F₃N₆O₂

CAS No.
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
MRTX1133
Cat. No.:
HY-134813
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