2. GPCR/G Protein
  3. Ras
  4. RAS-IN-2

RAS-IN-2 

Cat. No.: HY-148439
Handling Instructions

RAS-IN-2 (Compound A122) is a potent RAS(ON)MULTI inhibitor and can be used for the research of cancer.

For research use only. We do not sell to patients.

RAS-IN-2 Chemical Structure

RAS-IN-2 Chemical Structure

CAS No. : 2765081-21-6

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K-Ras H-Ras Ras

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Description

RAS-IN-2 (Compound A122) is a potent RAS(ON)MULTI inhibitor and can be used for the research of cancer[1].

IC50 & Target[1]

KRas G12D

 

In Vitro

RAS-IN-2 (Compound A122) (5 days) inhibits cell viability with an IC50 of 1-10 μM against AsPC-1 (K-Ras G12D)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

811.05

Formula

C44H58N8O5S
CAS No.
SMILES

CC(COC([[email protected]]1NN(C([[email protected]](CC2=NC3=CS2)NC([[email protected]]4C[[email protected]@H]4C)=O)=O)CCC1)=O)(C)CC5=[[email protected]@](N(CC)C6=C5C=C3C=C6)[[email protected]@]7=C([[email protected]](C)OC)N=CC(N8CCN(C)CC8)=C7
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

RAS-IN-22765081-21-6RasG12DK-RasAsPC-1Inhibitorinhibitorinhibit

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