1. PROTAC
    Protein Tyrosine Kinase/RTK
  2. SNIPER
    Bcr-Abl
  3. SNIPER(ABL)-049

SNIPER(ABL)-049 

Cat. No.: HY-111851
Handling Instructions

SNIPER(ABL)-049, conjugating Imatinib (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 100 μM.

For research use only. We do not sell to patients.

SNIPER(ABL)-049 Chemical Structure

SNIPER(ABL)-049 Chemical Structure

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Description

SNIPER(ABL)-049, conjugating Imatinib (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 100 μM[1].

Molecular Weight

959.14

Formula

C₅₂H₆₆N₁₀O₈

SMILES

CC1=CC=C(NC(C2=CC=C(CN3CCN(C(COCCOCCOCCNC([[email protected]](CC(C)C)NC([[email protected]@H](O)[[email protected]@H](CC4=CC=CC=C4)N)=O)=O)=O)CC3)C=C2)=O)C=C1NC5=NC=CC(C6=CC=CN=C6)=N5

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
SNIPER(ABL)-049
Cat. No.:
HY-111851
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