1 Result for "

apg-1387

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "apg-1387" in MCE Product Catalog:

Cat. No.: HY-125593
CAS No.: 1570231-89-8
Purity:  99.36%
Synonyms: apg-1387
Target:  

IAP Apoptosis

Research Areas:  

Cancer

Dasminapant (APG-1387), a bivalent SMAC mimetic and an IAP antagonist, blocks the activity of IAPs family proteins (XIAP, cIAP-1, cIAP-2, and ML-IAP). Dasminapant induces degradation of cIAP-1 and XIAP proteins, as well as caspase-3 activation and PARP cleavage, which leads to apoptosis. Dasminapant can be used for the research of hepatocellular carcinoma, ovarian cancer, and nasopharyngeal carcinoma .
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