1. PROTAC
    Protein Tyrosine Kinase/RTK
  2. SNIPER
    Bcr-Abl
  3. SNIPER(ABL)-044

SNIPER(ABL)-044 

Cat. No.: HY-111862
Handling Instructions

SNIPER(ABL)-044, conjugating HG-7-85-01 (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 μM.

For research use only. We do not sell to patients.

SNIPER(ABL)-044 Chemical Structure

SNIPER(ABL)-044 Chemical Structure

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Description

SNIPER(ABL)-044, conjugating HG-7-85-01 (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 μM[1].

Molecular Weight

1020.17

Formula

C₅₁H₆₄F₃N₉O₈S

SMILES

CCN1CCN(CC2=C(C(F)(F)F)C=C(NC(C3=CC(C4=NC5=C(N=C(NC(COCCOCCOCCNC([[email protected]](CC(C)C)NC([[email protected]@H](O)[[email protected]@H](CC6=CC=CC=C6)N)=O)=O)=O)S5)C=C4)=CC=C3)=O)C=C2)CC1

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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KeyWords:

SNIPER(ABL)-044 | SNIPER | Bcr-Abl | IAP-dependent Protein Eraser, Specific and Nongenetic inhibitor of apoptosis protein [IAP]-dependent Protein Eraser | Inhibitor | inhibitor | inhibit

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SNIPER(ABL)-044
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HY-111862
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