1. PROTAC
    Others
  2. SNIPER
    Estrogen Receptor/ERR
  3. SNIPER(ER)-110

SNIPER(ER)-110 

Cat. No.: HY-122825
Handling Instructions

SNIPER(ER)-110 consists of a cIAP1 ligand and an estrogen ligand, connected by a linker. SNIPER(ER)-51 induces estrogen receptor (ER) protein degradation with DC50s of <3 nM and 7.7 nM after 4 h and 48 h, respectively.

For research use only. We do not sell to patients.

SNIPER(ER)-110 Chemical Structure

SNIPER(ER)-110 Chemical Structure

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Description

SNIPER(ER)-110 consists of a cIAP1 ligand and an estrogen ligand, connected by a linker. SNIPER(ER)-51 induces estrogen receptor (ER) protein degradation with DC50s of <3 nM and 7.7 nM after 4 h and 48 h, respectively[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

1122.39

Formula

C₆₆H₈₃N₅O₁₁

SMILES

O=C([[email protected]]1N(C([[email protected]](C2CCCCC2)NC([[email protected]@H](NC)C)=O)=O)C[[email protected]@H](OC3=CC=CC(OCCOCCOCCOCC(N(C)CCOC4=CC=C(/C(C5=CC=C(O)C=C5)=C(C6=CC=CC=C6)/CC)C=C4)=O)=C3)C1)N[[email protected]@H]7CCCC8=C7C=CC=C8

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
SNIPER(ER)-110
Cat. No.:
HY-122825
Quantity:

SNIPER(ER)-110

Cat. No.: HY-122825