1. Apoptosis
  2. IAP
  3. SM-433

SM-433 

Cat. No.: HY-138059
Handling Instructions

SM-433, a Smac mimetic, function as inhibitor of inhibitor of apoptosis proteins (IAPs). SM-433 exhibits strong binding affinity XIAP BIR3 protein with an IC50<1 μM. (patent WO2008128171A2).

For research use only. We do not sell to patients.

SM-433 Chemical Structure

SM-433 Chemical Structure

CAS No. : 1071992-81-8

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Description

SM-433, a Smac mimetic, function as inhibitor of inhibitor of apoptosis proteins (IAPs). SM-433 exhibits strong binding affinity XIAP BIR3 protein with an IC50<1 μM. (patent WO2008128171A2)[1].

In Vitro

SM-433 exhibits strong inhibitory activity against MDA-MB -2131 human breast cancer cells and SK-OV-3 ovarian cancer cells (IC50s<10 μM, respectively)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

561.71

Formula

C₃₂H₄₃N₅O₄

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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SM-433
Cat. No.:
HY-138059
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