2. Productos naturales
  3. Plants
  4. Euphorbiaceae
  5. Euphorbia fischeriana Steud.

Euphorbia fischeriana Steud.

Euphorbia fischeriana Steud. (14):

Cat. No. Nombre del producto No. CAS Pureza Estructura química
  • HY-N0732
    Jolkinolide B 37905-08-1 99.65%
    Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud with oral activity. Jolkinolide B downregulates XIAP, cIAP1, cIAP2, and phosphorylated Akt, upregulates Smac, activates caspase-3 and caspase-9, and inhibits NF-κB, TGFβ/smad3 and JAK/STAT3 pathways. Jolkinolide B exerts comprehensive biological effects including inducing cancer cell apoptosis, suppressing inflammatory responses, improving lung function, alleviating hepatic steatosis and eliminating intracellular Mycobacterium tuberculosis. Jolkinolide B can be used for the research of leukemia, histiocytic lymphoma, asthma, metabolic dysfunction-associated steatotic liver disease and tuberculosis.
    Jolkinolide B
  • HY-N13201
    12-Deoxyphorbol 13-palmitate 66583-59-3 99.85%
    12-Deoxyphorbol 13-palmitate is a traditional Chinese medicine monomer with antitumor activity that can be isolated from the root of Euphorbia fischeriana. 12-Deoxyphorbol 13-palmitate induces gastric cancer cell cycle arrest and apoptosis by regulating key cell cycle regulators such as cyclin B、cyclin A and CDC2. In addition, 12-Deoxyphorbol 13-palmitate can significantly weaken APOL2–SERCA2–PERK–HES1 signaling and slow liver fibrosis by targeting APOL2.
    12-Deoxyphorbol 13-palmitate
  • HY-N19376
    17-Hydroxyjolkinolide B 247037-88-3
    17-Hydroxyjolkinolide B is a diterpenoid found in Euphorbia fischeriana Steud. 17-Hydroxyjolkinolide B exhibits bioactivities.
    17-Hydroxyjolkinolide B
  • HY-N11736
    12-O-Tiglyl-phorbol 13-dodecanoate 37394-32-4
    12-O-Tiglyl-phorbol 13-dodecanoate (TD13) is a potential inhibitor with anti-hepatic fibrosis activity, and it belongs to a series of derivatives of oral APOL2 inhibitors and anti-hepatic fibrosis agents. It shows no obvious toxicity in preclinical models. Compounds of the 12-O-Tiglyl-phorbol 13-dodecanoate series inhibit the expression of fibronectin, type I collagen and α-smooth muscle actin in hepatic stellate cells. 12-O-Tiglyl-phorbol 13-dodecanoate can be isolated from the Euphorbiaceae plant Euphorbia fischeriana, and it is applicable to the research of hepatic fibrosis.
    12-O-Tiglyl-phorbol 13-dodecanoate
  • HY-N17215
    3,4,6-Tri-O-galloyl-D-glucose 99523-99-6
    3,4,6-Tri-O-galloyl-D-glucose (3,4,6-Trigalloylglucose) is an α-amylase (porcine α-amylase IC50 = 334.6 μM; Ki = 307.5 μM) and α-glucosidase (yeast α-glucosidase IC50 = 46.5 μM; Ki = 39.9 μM) mixed type inhibitor. 3,4,6-Tri-O-galloyl-D-glucose exhibits free radical scavenging ability, ferric-reducing power, and antioxidant activity. 3,4,6-Tri-O-galloyl-D-glucose can be used for the research of diabetes.
    3,4,6-Tri-O-galloyl-D-glucose
  • HY-N17321
    7β-Hydroxystigmasterol 64998-20-5
    7β-Hydroxystigmasterol is a natural product that can be found in soybeans.
    7β-Hydroxystigmasterol
  • HY-N0732R
    Jolkinolide B (Standard) 37905-08-1
    Jolkinolide B (Standard) is the analytical standard of Jolkinolide B (HY-N0732). This product is intended for research and analytical applications. Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud with oral activity. Jolkinolide B downregulates XIAP, cIAP1, cIAP2, and phosphorylated Akt, upregulates Smac, activates caspase-3 and caspase-9, and inhibits NF-κB, TGFβ/smad3 and JAK/STAT3 pathways. Jolkinolide B exerts comprehensive biological effects including inducing cancer cell apoptosis, suppressing inflammatory responses, improving lung function, alleviating hepatic steatosis and eliminating intracellular Mycobacterium tuberculosis. Jolkinolide B can be used for the research of leukemia, histiocytic lymphoma, asthma, metabolic dysfunction-associated steatotic liver disease and tuberculosis.
    Jolkinolide B (Standard)
  • HY-N12428
    17-Hydroxyjolkinolide A 65388-16-1
    17-Hydroxyjolkinolide A (Caudicifolin; Fischeriana A) is an insect feeding inhibitor isolated from the roots of spurge. 17-Hydroxyjolkinolide A induces grain aversion in S. zeamais and T. castaneum adults, with EC50s of 631.9 ppm and 656.5 ppm, respectively.
    17-Hydroxyjolkinolide A
  • HY-N10046
    ent-17-Hydroxykauran-3-one 960589-81-5
    ent-17-Hydroxykauran-3-one (ent-Kaurane-3-oxo-17β-ol; compound 7) is a kaurane-type diterpenoid that can be found in the roots of Euphorbia fischeriana.
    ent-17-Hydroxykauran-3-one
  • HY-N10875
    Euphebracteolatin B 768402-09-1
    Euphebracteolatin B is a nature product that could be isolated from Euphorbia fischeriana.
    Euphebracteolatin B
  • HY-N9280
    ent-11α-Hydroxyabieta-8(14),13(15)-dien-16,12α-olide 130466-20-5
    ent-11α-Hydroxyabieta-8(14),13(15)-dien-16,12α-olide (compound 12) is a natural bioactive diterpenoid found in the roots of Euphorbia fischeriana.
    ent-11α-Hydroxyabieta-8(14),13(15)-dien-16,12α-olide
  • HY-119767
    Jolkinolide A 37905-07-0 98.0%
    Jolkinolide A is a diterpenoid, can be extracted from the roots of Euphorbia fischeriana Steud. Jolkinolide A exhibits anti-tumor activity, by affecting on angiogenesis of tumor tissues. Jolkinolide A significantly inhibits the Akt-STAT3-mTOR signaling pathway and reduces the expression of VEGF in A549 cells.
    Jolkinolide A
  • HY-N2880
    Antiquorin 125356-08-3
    Antiquorin is a Diterpenoids product that can be isolated from the roots of Euphorbia fischeriana..
    Antiquorin
  • HY-N1897
    4-Hydroxy-11,12,13-trinor-5-eudesmen-7-one 133369-42-3
    4-Hydroxy-11,12,13-trinor-5-eudesmen-7-one is a Sesquiterpenoids product that can be isolated from the roots of Euphorbia fischeriana..
    4-Hydroxy-11,12,13-trinor-5-eudesmen-7-one