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Cat. No.: HY-N12428

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17-Hydroxyjolkinolide A

(Synonyms: Caudicifolin; Fischeriana A)

17-Hydroxyjolkinolide A (Caudicifolin; Fischeriana A) is an insect feeding inhibitor isolated from the roots of spurge. 17-Hydroxyjolkinolide A induces grain aversion in S. zeamais and T. castaneum adults, with EC₅₀s of 631.9 ppm and 656.5 ppm, respectively.

For research use only. We do not sell to patients.

CAS No.: 65388-16-1
Formula: C₂₀H₂₆O₄
Molecular Weight:330.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

17-Hydroxyjolkinolide A Chemical Structure

CAS No.: 65388-16-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
BV-2	IC₅₀	9.1 μM Compound: 14	Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by Griess assay Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by Griess assay	[PMID: 31180680]
HCT-15	IC₅₀	13 μM Compound: 6e	Cytotoxicity against human HCT-15 cells incubated for 48 hrs by MTT assay Cytotoxicity against human HCT-15 cells incubated for 48 hrs by MTT assay	[PMID: 33289552]
LNCaP C4-2B	IC₅₀	2.2 μM Compound: 6e	Cytotoxicity against human LNCaP C4-2B cells incubated for 48 hrs by MTT assay Cytotoxicity against human LNCaP C4-2B cells incubated for 48 hrs by MTT assay	[PMID: 33289552]
MDA-MB-231	IC₅₀	8.8 μM Compound: 6e	Cytotoxicity against human MDA-MB-231 cells incubated for 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells incubated for 48 hrs by MTT assay	[PMID: 33289552]

Chemical Information

CAS No. 65388-16-1
Molecular Weight 330.42
Formula C₂₀H₂₆O₄
SMILES

C[C@]12[C@@]3([H])[C@@]4(CC[C@]1([H])C(C)(CCC2)C)[C@](C(C(O5)=C3)=C(CO)C5=O)([H])O4
Synonyms

Caudicifolin; Fischeriana A
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Geng ZF, et al.Feeding deterrents against two grain storage insects from Euphorbia fischeriana. Molecules. 2011 Jan 10;16(1):466-76. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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