Liensinine (Standard)
Liensinine (Standard) is the analytical standard of Liensinine (HY-N0484). This product is intended for research and analytical applications. Liensinine is a bisbenzylisoquinoline alkaloid. By inhibiting the PI3K/AKT and JNK/p38-MAPK signaling pathways, Liensinine suppresses autophagy and apoptosis, clears Aβ, and exerts anti-inflammatory, antioxidant and neuroprotective effects. Liensinine activates AMPK and inhibits the expression of HIF-1α and VEGF, thereby suppressing angiogenesis. Liensinine exerts anti-tumor effects through ROS-mediated inhibition of the JAK2/STAT3 signaling pathway. Liensinine can be used for the research of diseases such as Alzheimer's disease, hepatocellular carcinoma, osteosarcoma, sepsis-induced organ injury and stroke.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98%
- CAS 番号: 2586-96-1
- 分子式: C37H42N2O6
- 分子量:610.74
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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化学情報
- 純度とドキュメンテーション
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Help & FAQs
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HY-N0484
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Product Information
説明
アプリケーション
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
化学情報
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CAS 番号 2586-96-1
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分子量 610.74
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分子式 C37H42N2O6
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SMILES
OC1=CC=C(C[C@H]2N(C)CCC3=C2C=C(OC)C(OC)=C3)C=C1OC4=CC5=C(C=C4OC)CCN(C)[C@@H]5CC6=CC=C(O)C=C6
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Liensinine (Standard) 関連分類
HY-N0484R 関連分類
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Keywords
- Liensinine (Standard)
- 2586-96-1
- PI3K
- Reference Standards
- Apoptosis
- Amyloid-β
- STAT
- Akt
- Autophagy
- JAK
- HIF/HIF Prolyl-Hydroxylase
- JNK
- Reactive Oxygen Species (ROS)
- VEGFR
- p38 MAPK
- Phosphoinositide 3-kinase
- β-amyloid peptide
- Aβ
- Abeta
- PKB
- Protein kinase B
- Janus kinase
- Hypoxia-inducible factors
- HIFs
- HIF-PH
- c-Jun N-terminal kinase
- Vascular endothelial growth factor receptor
- apoptosis
- autophagy
- autophagic
- stress
- breast
- cancer
- DNM1L
- lysosome
- mitochondrial
- fission
- RAB7A
- Inhibitor
- inhibitor
- inhibit