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Referencia número: HY-N0484R

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Liensinine (Standard)

Name: Liensinine (Standard)
Brand: MedChemExpress
SKU: HY-N0484R
Price: 125.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Liensinine (Standard) is the analytical standard of Liensinine (HY-N0484). This product is intended for research and analytical applications. Liensinine is a bisbenzylisoquinoline alkaloid. By inhibiting the PI3K/AKT and JNK/p38-MAPK signaling pathways, Liensinine suppresses autophagy and apoptosis, clears Aβ, and exerts anti-inflammatory, antioxidant and neuroprotective effects. Liensinine activates AMPK and inhibits the expression of HIF-1α and VEGF, thereby suppressing angiogenesis. Liensinine exerts anti-tumor effects through ROS-mediated inhibition of the JAK2/STAT3 signaling pathway. Liensinine can be used for the research of diseases such as Alzheimer's disease, hepatocellular carcinoma, osteosarcoma, sepsis-induced organ injury and stroke.

Para uso exclusivo en investigación. No vendemos a pacientes.

Pureza: 98%
No. CAS: 2586-96-1
Fòrmula: C₃₇H₄₂N₂O₆
Peso molecular:610.74

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Liensinine (Standard) Chemical Structure

No. CAS: 2586-96-1

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Aplicación

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

No. CAS 2586-96-1
Peso molecular 610.74
Fòrmula C₃₇H₄₂N₂O₆
SMILES

OC1=CC=C(C[C@H]2N(C)CCC3=C2C=C(OC)C(OC)=C3)C=C1OC4=CC5=C(C=C4OC)CCN(C)[C@@H]5CC6=CC=C(O)C=C6
Structure Classification
- Alkaloids
- Alkaloid Dimers
- Phenols
- Polyphenols
Initial Source
- Plants
- other families
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Referencias

[1]. Zhou J, et al. A novel autophagy/mitophagy inhibitor liensinine sensitizes breast cancer cells to chemotherapy through DNM1L-mediated mitochondrial fission. Autophagy. 2015;11(8):1259-79. [Content Brief]

[2]. Liang Pang, et al. Protective effect of liensinine on periodontitis through its antioxidant effect in mice. Journal of the Korean Society for Applied Biological Chemistry volume 58, pages927-936

[3]. Shuhua Tong, et al. Pharmacokinetics and bioavailability of liensinine in mouse blood by UPLC-MS/MS. Acta Chromatographica,Volume 33: Issue 4,14 Oct 2020.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Liensinine (Standard)

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