1. Signaling Pathways
  2. Protein Tyrosine Kinase/RTK
  3. VEGFR
  4. VEGFR1/Flt-1 Inhibitors

VEGFR1/Flt-1 Inhibitors

VEGFR1/Flt-1

VEGFR2/KDR/Flk-1

VEGFR3/Flt-4

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform VEGFR1/Flt-1 together.

Please try each isoform separately.

VEGFR1/Flt-1 Specific Inhibitors
Product Name VEGFR1/Flt-1 VEGFR2/KDR/Flk-1 VEGFR3/Flt-4 VEGFR1/Flt-1 Selectivity Purity
PF-03814735
Flt-1, IC50: 10 nM
    Selective Inhibitor 99.77%
SU14813
VEGFR1, IC50: 2 nM
VEGFR2, IC50: 50 nM
  Selective Inhibitor 95.74%
SU14813 maleate
VEGFR1, IC50: 2 nM
VEGFR2, IC50: 50 nM
  Selective Inhibitor 99.34%
Orantinib
Flt-1, Ki: 2.1 μM
    Selective Inhibitor 99.02%
Lenvatinib
VEGFR1, IC50: 22 nM
VEGFR2, IC50: 4 nM
VEGFR3, IC50: 5.2 nM
Pan Inhibitor 99.74%
Nintedanib
VEGFR1, IC50: 34 nM
VEGFR2, IC50: 13 nM
VEGFR3, IC50: 13 nM
Pan Inhibitor 99.97%
Cabozantinib
Flt-1, IC50: 12 nM
VEGFR2, IC50: 0.035 nM
Flt-4, IC50: 6 nM
Pan Inhibitor 99.92%
Regorafenib
VEGFR1, IC50: 13 nM
VEGFR2, IC50: 4.2 nM
VEGFR3, IC50: 46 nM
Pan Inhibitor 99.96%
Axitinib
VEGFR1, IC50: 0.1 nM
VEGFR2, IC50: 0.2 nM
VEGFR3, IC50: 0.1 nM
Pan Inhibitor 99.94%
Cediranib
Flt-1, IC50: 5 nM
KDR, IC50: 1 nM
Flt-4, IC50: 3 nM
Pan Inhibitor 99.58%
Sitravatinib
VEGFR1, IC50: 6 nM
VEGFR2, IC50: 5 nM
VEGFR3, IC50: 2 nM
Pan Inhibitor 99.85%
Lucitanib
VEGFR1, IC50: 7 nM
VEGFR2, IC50: 25 nM
VEGFR3, IC50: 10 nM
Pan Inhibitor 98.24%
Tivozanib
VEGFR1, IC50: 30 nM
VEGFR2, IC50: 6.5 nM
VEGFR3, IC50: 15 nM
Pan Inhibitor 99.52%
Nintedanib esylate
VEGFR1, IC50: 34 nM
VEGFR2, IC50: 13 nM
VEGFR3, IC50: 13 nM
Pan Inhibitor 99.95%
Regorafenib Hydrochloride
VEGFR1, IC50: 13 nM
VEGFR2, IC50: 4.2 nM
VEGFR3, IC50: 46 nM
Pan Inhibitor 99.58%
Motesanib
VEGFR1, IC50: 2 nM
VEGFR2, IC50: 3 nM
VEGFR3, IC50: 6 nM
Pan Inhibitor 99.75%
Pazopanib Hydrochloride
VEGFR1, IC50: 10 nM
VEGFR2, IC50: 30 nM
VEGFR3, IC50: 47 nM
Pan Inhibitor 99.92%
Fruquintinib
VEGFR1, IC50: 33 nM
VEGFR2, IC50: 35 nM
VEGFR3, IC50: 0.5 nM
Pan Inhibitor 99.93%
TAK-593
VEGFR1, IC50: 3.2 nM
VEGFR2, IC50: 0.95 nM
VEGFR3, IC50: 1.1 nM
Pan Inhibitor 99.62%
Regorafenib monohydrate
VEGFR1, IC50: 13 nM
VEGFR2, IC50: 4.2 nM
VEGFR3, IC50: 46 nM
Pan Inhibitor 99.96%
Motesanib Diphosphate
VEGFR1, IC50: 2 nM
VEGFR2, IC50: 3 nM
VEGFR3, IC50: 6 nM
Pan Inhibitor 99.64%
Cediranib maleate
Flt-1, IC50: 5 nM
KDR, IC50: 1 nM
Flt-4, IC50: 3 nM
Pan Inhibitor 96.67%
ZM 306416
Flt-1, IC50: 2 μM
KDR, IC50: 100 nM
  Pan Inhibitor 99.80%
NVP-ACC789
VEGFR-1, IC50: 0.38 μM
VEGFR-2, IC50: 0.02 μM
mVEGFR-2, IC50: 0.23 μM
VEGFR-3, IC50: 0.18 μM
Pan Inhibitor 99.58%
NVP-BAW2881
VEGFR1, IC50: 820 nM
VEGFR2, IC50: 9 nM
VEGFR3, IC50: 420 nM
Pan Inhibitor 98.42%
KRN-633
VEGFR1, IC50: 170 nM
VEGFR2, IC50: 160 nM
VEGFR3, IC50: 125 nM
Pan Inhibitor 99.06%
Ilorasertib
VEGFR1, IC50: 1 nM
VEGFR2, IC50: 2 nM
VEGFR3, IC50: 43 nM
Pan Inhibitor
Tyrosine kinase-IN-1
Flt-1, IC50: 4 nM
KDR, IC50: 20 nM
  Pan Inhibitor 99.47%
ODM-203
VEGFR1, IC50: 26 nM
VEGFR2, IC50: 9 nM
VEGFR3, IC50: 5 nM
Pan Inhibitor
Sulfatinib
VEGFR1
VEGFR2
VEGFR3
default Inhibitor 97.97%
SCR-1481B1
VEGFR1
    default Inhibitor 99.99%
SKLB610
VEGFR1
    default Inhibitor 98.96%