2. Signaling Pathways
  3. Protein Tyrosine Kinase/RTK
  4. VEGFR
  5. VEGFR1/Flt-1 Isoform
  6. VEGFR1/Flt-1 Activator

VEGFR1/Flt-1 Activator

VEGFR1/Flt-1 Activator (1):

Cat. No. Product Name Effect Purity
  • HY-P3226
    JB-1
    		Activator 99.63%
    JB-1, an IGF-I analog, is a selective IGF-I receptor inhibitor that does not interact with IGF-II. JB-1 competes with IGF-I for binding to IGF-1R and blocks receptor autophosphorylation. JB-1 increases the level of sVEGFR-1. JB-1 normalizes retinal abnormalities, including reducing retinal neovascularization. JB-1 is applicable to studies related to oxygen-induced retinopathy.