2. Cytoskeleton Protein Tyrosine Kinase/RTK
  3. Integrin VEGFR
  4. NYLTHRQ

NYLTHRQ is a peptide. NYLTHRQ specifically blocks the interaction between sVEGFR1-i13 and β1 integrin, and inhibits the activation of VEGFR1 and VEGFR2. NYLTHRQ inhibits cancer cell proliferation. NYLTHRQ can be used in the research of tumors such as lung squamous cell carcinoma.

For research use only. We do not sell to patients.

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NYLTHRQ

NYLTHRQ Chemical Structure

CAS No. : 1004284-41-6

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NYLTHRQ Related Antibodies

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Description

NYLTHRQ is a peptide. NYLTHRQ specifically blocks the interaction between sVEGFR1-i13 and β1 integrin, and inhibits the activation of VEGFR1 and VEGFR2. NYLTHRQ inhibits cancer cell proliferation. NYLTHRQ can be used in the research of tumors such as lung squamous cell carcinoma[1].

IC50 & Target[1]

VEGFR1

 

VEGFR2

 

In Vitro

NYLTHRQ (10 μg/mL; 72 h) specifically blocks the interaction between sVEGFR1-i13 and β1 integrin in MGH7 cells, inhibits VEGFR activation, and reduces cell proliferation activity[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

NYLTHRQ Related Antibodies

Cell Proliferation Assay[1]

Cell Line: MGH7 squamous cell lung carcinoma (SQLC) cells
Concentration: 10 μg/mL
Incubation Time: 72 h
Result: Prevented the activation of VEGFR1 (Tyr1213) and VEGFR2 (Tyr1214) proteins.
Blocked the increased cell proliferation induced by sVEGFR1-i13-containing conditioned supernatants.
Molecular Weight

931.01

Formula

C40H62N14O12
CAS No.
Sequence

Asn-Tyr-Leu-Thr-His-Arg-Gln
Sequence Shortening

NYLTHRQ
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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NYLTHRQ Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NYLTHRQ1004284-41-6IntegrinVEGFRVascular endothelial growth factor receptorVEGFR1lung squamous cell carcinoma cellsMGH7 SQLC cellsβ1 integrinVEGFR2squamous cell lung carcinomasVEGFR1-i13Inhibitorinhibitorinhibit

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