1. Signaling Pathways
  2. MAPK/ERK Pathway
  3. JNK
  4. JNK2 Isoform

JNK2

 

JNK2 Related Products (19):

Cat. No. Product Name Effect Purity
  • HY-12041
    SP600125
    Inhibitor 99.55%
    SP600125 is an orally active, reversible, and ATP-competitive JNK inhibitor with IC50s of 40, 40 and 90 nM for JNK1, JNK2 and JNK3, respectively.
  • HY-13319
    JNK-IN-8
    Inhibitor 99.65%
    JNK-IN-8 (JNK Inhibitor XVI) is a potent JNK inhibitor with IC50s of 4.7 nM, 18.7 nM, and 1 nM for JNK1, JNK2, and JNK3, respectively.
  • HY-15495
    Tanzisertib
    Inhibitor 99.87%
    Tanzisertib (CC-930) is a potent JNK1/2/3 inhibitor with IC50s of 61/7/6 nM, respectively.
  • HY-138304
    CC-90001
    Inhibitor 99.85%
    CC-90001 is a potent, selective and orally active inhibitor of c-Jun N-terminal kinase (JNK).
  • HY-11010
    AS601245
    Inhibitor 98.70%
    AS601245 is an orally active, selective, ATP competitive JNK (c-Jun NH2-terminal protein kinase) inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively.
  • HY-150053
    JNK-IN-11
    Inhibitor
    JNK-IN-11 (compound 1) is a potent JNK inhibitor with an IC50 value of 2.2, 21.4, 1.8 µM for JNK1, JNK2, JNK3, respectively.
  • HY-150688
    JAK3-IN-13
    Inhibitor
    JAK3-IN-13 is a potent, selective and orally active JAK3 inhibitor with IC50 values of 4728, 2039, 8, 365 nM for NK1, JNK2, JNK3, Tyk2, respectively.
  • HY-150552
    JNK3 inhibitor-2
    Inhibitor
    JNK3 inhibitor-2 is a potent and selective JNK3 inhibitor with IC50 values of >100, >100, 0.25 µM for JNK1, JNK2, JNK3, respectively.
  • HY-14761
    Bentamapimod
    Inhibitor 99.52%
    Bentamapimod (AS 602801) is an ATP-competitive JNK inhibitor with IC50 of 80 nM, 90 nM, and 230 nM for JNK1, JNK2, and JNK3, respectively.
  • HY-107598
    JNK Inhibitor VIII
    Inhibitor 99.56%
    JNK Inhibitor VIII (TCS JNK 6o) is a c-Jun N-terminal kinases (JNK-1, -2, and -3) inhibitor with Ki values of 2 nM, 4 nM, 52 nM, respectively, and has IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively.
  • HY-N0773
    Isovitexin
    Inhibitor 99.95%
    Isovitexin is a flavonoid isolated from passion flower, Cannabis and, and the palm, possesses anti-inflammatory and anti-oxidant activities; Isovitexin acts like a JNK1/2 inhibitor and inhibits the activation of NF-κB.
  • HY-15617
    JNK-IN-7
    Inhibitor 98.41%
    JNK-IN-7 is a potent JNK inhibitor with IC50 of 1.5, 2 and 0.7 nM for JNK1, JNK2 and JNK3, respectively.
  • HY-100233
    IQ-1S free acid
    Inhibitor 99.35%
    IQ-1S free acid is a prospective inhibitor of NF-κB/activating protein 1 (AP-1) activity with an IC50 of 2.3±0.41 μM.
  • HY-107600
    IQ-3
    Inhibitor 98.91%
    IQ-3 is a specific inhibitor of the c-Jun N-terminal kinase (JNK) family, with preference for JNK3.
  • HY-15881
    TCS JNK 5a
    Inhibitor 98.96%
    TCS JNK 5a is a potent JNK3 inhibitor with a pIC50 of 6.7.
  • HY-N7394A
    (-)-Zuonin A
    Inhibitor 99.84%
    (-)-Zuonin A (D-Epigalbacin), a naturally occurring lignin, is a potent, selective JNKs inhibitor, with IC50s of 1.7 μM, 2.9 μM and 1.74 μM for JNK1, JNK2 and JNK3, respectively.
  • HY-P2247
    JTP10-△-R9 TFA
    Inhibitor 99.80%
    JTP10-△-R9 TFA is a selective JNK2 peptide inhibitor, with an IC50 of 89 nM, exhibiting 10-fold selectivity for JNK2 over JNK1 and JNK3.
  • HY-139254
    Indirubin-3′-oxime
    Inhibitor 99.49%
    Indirubin-3′-oxime (IDR3O), a synthetic derivative of indirubin, is a potent inhibitor of cyclin-dependent kinases (CDKs) and glycogen synthase kinase 3β (GSK3β).
  • HY-P2246
    JTP10-△-TATi TFA
    Inhibitor
    JTP10-△-TATi TFA is a selective JNK2 peptide inhibitor, with an IC50 of 92 nM, exhibiting 10-fold selectivity for JNK2 over JNK1 and JNK3.