23146-22-7
23146-22-7
Chemical Structure
IQ-1S free acid
- CAS No.: 23146-22-7
- Formula:C15H9N3O
- Molecular Weight:247.25
IUPAC Name: (E)-11H-indeno[1,2-b]quinoxalin-11-one oxime
InChIKey: SZHHSFHOIDCNLD-NBVRZTHBSA-N
SMILES: O/N=C1C2=C(C3=NC4=CC=CC=C4N=C3\1)C=CC=C2
Biological Activity: IQ-1S free acid is a prospective inhibitor of NF-κB/activating protein 1 (AP-1) activity with an IC50 of 2.3±0.41 μM. IQ-1S free acid has binding affinity (Kd values) in the nanomolar range for all three JNKs with Kds of 100 nM, 240 nM, and 360 nM for JNK3, JNK1, and JNK2, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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IQ-1S free acid | 99.28% | IQ-1S free acid is a prospective inhibitor of NF-κB/activating protein 1 (AP-1) activity with an IC50 of 2.3±0.41 μM. IQ-1S free acid has binding affinity (Kd values) in the nanomolar range for all three JNKs with Kds of 100 nM, 240 nM, and 360 nM for JNK3, JNK1, and JNK2, respectively. | ||||||||||||||||||||
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IQ-1S free acid (Standard) | ≥98% | IQ-1S (free acid) (Standard) is the analytical standard of IQ-1S (free acid) (HY-100233). This product is intended for research and analytical applications. IQ-1S free acid is a prospective inhibitor of NF-κB/activating protein 1 (AP-1) activity with an IC50 of 2.3±0.41 μM. IQ-1S free acid has binding affinity (Kd values) in the nanomolar range for all three JNKs with Kds of 100 nM, 240 nM, and 360 nM for JNK3, JNK1, and JNK2, respectively. | ||||||||||||||||||||
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