1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. SGK
  4. SGK1 Isoform

SGK1

 

SGK1 Related Products (4):

Cat. No. Product Name Effect Purity
  • HY-15192
    GSK 650394
    Inhibitor 99.76%
    GSK 650394 is a novel SGK inhibitor with IC50 of 62 nM and 103 nM for SGK1 and SGK2 in the SPA assay respectively. GSK 650394 also inhibits influenza virus replication.
  • HY-15193
    EMD638683
    Inhibitor 99.89%
    EMD638683 is a highly selective SGK1 inhibitor, with an IC50 value of 3 μM.
  • HY-18607
    SGK1-IN-1
    Inhibitor 99.67%
    SGK1-IN-1 is a highly active and selective inhibitor of SGK-1, with an IC50 of 1 nM.
  • HY-142686
    SGK1-IN-3
    Inhibitor
    SGK1-IN-3 (compound 3a) is a potent and orally active inhibitor of SGK1. The serine/threonine kinase SGK1 is an activator of the β-catenin pathway and a powerful stimulator of cartilage degradation that is found to be upregulated under genomic control in diseased osteoarthritic cartilage. SGK1-IN-3 has the potential for the research of osteoarthritis.