SGK2
SGK2 is the middle member of the serum- and glucocorticoid-regulated kinase family and the least studied of the three SGK isoforms. It shares the AGC kinase fold and PDK1-dependent activation mechanism of SGK1 and SGK3 but shows lower overall expression, with notable transcript levels in kidney, brain and testis, and lacks a PX membrane-targeting domain. Reported activities include phosphorylation of FOXO3, which is shared with SGK1, and roles in ion transport and cell survival. Because SGK2 expression responds to stimuli differently than SGK1, recombinant SGK2 helps dissect isoform-specific functions within the SGK subfamily of PI3K-activated kinases.
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SGK2 Recombinant Proteins (2)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
