894804-07-0
894804-07-0
Chemical Structure
JNK Inhibitor VIII
Synonym(s): TCS JNK 6o
- CAS No.: 894804-07-0
- Formula:C18H20N4O4
- Molecular Weight:356.38
IUPAC Name: N-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-dimethoxyphenyl)acetamide
InChIKey: KQMPRSZTUSSXND-UHFFFAOYSA-N
SMILES: N#CC1=C(N=C(NC(CC2=C(C=CC(OC)=C2)OC)=O)C=C1N)OCC
Biological Activity: JNK Inhibitor VIII (TCS JNK 6o) is a c-Jun N-terminal kinases (JNK-1, -2, and -3) inhibitor with Ki values of 2 nM, 4 nM, 52 nM, respectively, and has IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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JNK Inhibitor VIII | 99.58% | JNK Inhibitor VIII (TCS JNK 6o) is a c-Jun N-terminal kinases (JNK-1, -2, and -3) inhibitor with Ki values of 2 nM, 4 nM, 52 nM, respectively, and has IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively. | ||||||||||||||||||||
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JNK Inhibitor VIII (Standard) | ≥98% | JNK Inhibitor VIII (Standard) is the analytical standard of JNK Inhibitor VIII (HY-107598). This product is intended for research and analytical applications. JNK Inhibitor VIII (TCS JNK 6o) is a c-Jun N-terminal Kinases (JNK-1, -2, and -3) inhibitor with Ki values of 2 nM, 4 nM, 52 nM, respectively, and has IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.50
HY-121611HI-236 -
Similarity Score 0.49
HY-128433CK1-IN-3 -
Similarity Score 0.48
HY-13035125H-NBOMe hydrochloride -
Similarity Score 0.48
HY-17068325H-NB4OMe hydrochloride -
Similarity Score 0.47
HY-11474625H-NBOMe imine analog -
Similarity Score 0.47
HY-W72215525H-NBOH hydrochloride -
Similarity Score 0.47
HY-110115TC-Mps1-12 -
Similarity Score 0.46
HY-106434Piritrexim -
Similarity Score 0.46
HY-10312725CN-NBOH hydrochloride -
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