1. MAPK/ERK Pathway
  2. JNK
  3. JNK Inhibitor VIII

JNK Inhibitor VIII (Synonyms: TCS JNK 6o)

Cat. No.: HY-107598
Handling Instructions

JNK Inhibitor VIII (TCS JNK 6o) is a c-Jun N-terminal kinases (JNK-1, -2, and -3) inhibitor with Ki values of 2 nM, 4 nM, 52 nM, respectively.

For research use only. We do not sell to patients.

JNK Inhibitor VIII Chemical Structure

JNK Inhibitor VIII Chemical Structure

CAS No. : 894804-07-0

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Estimated Time of Arrival: December 31
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Description

JNK Inhibitor VIII (TCS JNK 6o) is a c-Jun N-terminal kinases (JNK-1, -2, and -3) inhibitor with Ki values of 2 nM, 4 nM, 52 nM, respectively[1].

IC50 & Target[1]

JNK1

2 nM (Ki)

JNK2

4 nM (Ki)

JNK3

52 nM (Ki)

In Vitro

JNK Inhibitor VIII (TCS JNK 6o) shows over 1000- fold selective for JNK-1 and -2 over other MAP kinases including ERK2, p38α, and p38δ[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

356.38

Formula

C₁₈H₂₀N₄O₄

CAS No.

894804-07-0

SMILES

N#CC1=C(N=C(NC(CC2=C(C=CC(OC)=C2)OC)=O)C=C1N)OCC

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
JNK Inhibitor VIII
Cat. No.:
HY-107598
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JNK Inhibitor VIII

Cat. No.: HY-107598