1410880-22-6
1410880-22-6
Chemical Structure
JNK-IN-8
Synonym(s): JNK Inhibitor XVI
- CAS No.: 1410880-22-6
- Formula:C29H29N7O2
- Molecular Weight:507.59
IUPAC Name: (E)-3-(4-(dimethylamino)but-2-enamido)-N-(3-methyl-4-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
InChIKey: GJFCSAPFHAXMSF-UXBLZVDNSA-N
SMILES: CC1=CC(NC(C2=CC=CC(NC(/C=C/CN(C)C)=O)=C2)=O)=CC=C1NC3=NC=CC(C4=CN=CC=C4)=N3
Biological Activity: JNK-IN-8 (JNK Inhibitor XVI) is a potent JNK inhibitor with IC50s of 4.7 nM, 18.7 nM, and 1 nM for JNK1, JNK2, and JNK3, respectively[1].
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JNK-IN-8 | 99.67% | JNK-IN-8 (JNK Inhibitor XVI) is a potent JNK inhibitor with IC50s of 4.7 nM, 18.7 nM, and 1 nM for JNK1, JNK2, and JNK3, respectively. | ||||||||||||||||||||
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JNK-IN-8 (GMP) | JNK-IN-8 (JNK Inhibitor XVI) (GMP) is JNK-IN-8 (HY-13319) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. JNK-IN-8 is a potent JNK inhibitor with IC50s of 4.7 nM, 18.7 nM, and 1 nM for JNK1, JNK2, and JNK3, respectively. | |||||||||||||||||||||
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References
Keywords
