518-94-5
518-94-5
Chemical Structure
Cycleanine
- CAS No.: 518-94-5
- Formula:C38H42N2O6
- Molecular Weight:622.75
IUPAC Name: (11R,51R)-16,17,56,57-tetramethoxy-12,52-dimethyl-11,12,13,14,51,52,53,54-octahydro-2,6-dioxa-1(8,1),5(1,8)-diisoquinolina-3,7(1,4)-dibenzenacyclooctaphane
InChIKey: ANOXEUSGZWSCQL-LOYHVIPDSA-N
SMILES: COC1=C(OC2=CC=C(C[C@](N(CC3)C)([H])C4=C3C=C5OC)C=C2)C([C@@](N6C)([H])CC7=CC=C(OC4=C5OC)C=C7)=C(CC6)C=C1OC
Biological Activity: Cycleanine is a potent vascular selective Calcium antagonist. Cycleanine has analgesic, muscle relaxant and anti-inflammatory activities. Cycleanine has potential for anti-ovarian cancer acting through the apoptosis pathway[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Cycleanine | 99.80% | Cycleanine is a potent vascular selective Calcium antagonist. Cycleanine has analgesic, muscle relaxant and anti-inflammatory activities. Cycleanine has potential for anti-ovarian cancer acting through the apoptosis pathway. | ||||||||||||||||||||
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References
- [1]. Martínez JA, et al. Calcium antagonist properties of the bisbenzylisoquinoline alkaloid cycleanine. Fundam Clin Pharmacol. 1998;12(2):182-7. [Content Brief]
- [2]. Uche FI, et al. Cytotoxicity Effects and Apoptosis Induction by Bisbenzylisoquinoline Alkaloids from Triclisia subcordata. Phytother Res. 2016 Sep;30(9):1533-9. [Content Brief]
