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Apocynaceae

Apocynaceae (46):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0488
    Vincristine sulfate 2068-78-2 99.81%
    Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM.
    Vincristine sulfate
  • HY-12053A
    Vinorelbine ditartrate 125317-39-7 98.08%
    Vinorelbine (ditartrate) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM.
    Vinorelbine ditartrate
  • HY-13780
    Vinblastine sulfate 143-67-9 98.86%
    Vinblastine sulfate is a cytotoxic alkaloid used against various cancer types. Vinblastine sulfate inhibits the formation of microtubule and suppresses nAChR with an IC50 of 8.9 μM.
    Vinblastine sulfate
  • HY-N1445
    Isoquercetin 482-35-9 99.87%
    Isoquercetin (Quercetin 3-glucoside) is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties. Isoquercetin alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway. Isoquercetin regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system. Isoquercetin has high bioavailability and low toxicity, is a promising candidate agent to prevent birth defects in diabetic pregnancies.
    Isoquercetin
  • HY-N0768
    Isoquercitrin 21637-25-2 99.95%
    Isoquercitrin (Isoquercitroside) is an effective antioxidant and an eosinophilic inflammation suppressor.
    Isoquercitrin
  • HY-W012092
    Ethyl 3,4,5-trimethoxybenzoate 6178-44-5
    Ethyl 3,4,5-trimethoxybenzoate is a natural compound isolated from the roots of Rauvolfia yunnanensis Tsiang.
    Ethyl 3,4,5-trimethoxybenzoate
  • HY-N1248
    Scandine 24314-59-8
    Scandine is a alkaloid compound isolated from the twigs and leaves of Melodinus suaveolens.
    Scandine
  • HY-12715
    Yohimbine 146-48-5 98.10%
    Yohimbine is a potent and relatively nonselective alpha 2-adrenergic receptor (AR) antagonist, with IC50 of 0.6 μM.
    Yohimbine
  • HY-13295
    Vinpocetine 42971-09-5 99.77%
    Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na+ channels. The IC50 value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 μM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-κB-dependent inflammatory responses by directly targeting IκB kinase complex (IKK), and has been widely used for the treatment of cerebrovascular disorders.
    Vinpocetine
  • HY-15753A
    Ellipticine hydrochloride 5081-48-1 99.45%
    Ellipticine (NSC 71795) hydrochloride is a potent antineoplastic agent; inhibits DNA topoisomerase II activities.
    Ellipticine hydrochloride
  • HY-13719
    Oleandrin 465-16-7 99.44%
    Oleandrin (PBI-05204) inhibits the Na+, K+-ATPase activity with an IC50 of 620 nM.
    Oleandrin
  • HY-N2331
    Proscillaridin A 466-06-8 99.74%
    Proscillaridin A is a potent poison of topoisomerase I/II activity with IC50 values of 30 nM and 100 nM, respectively.
    Proscillaridin A
  • HY-W011151
    trans-Zeatinriboside 6025-53-2 99.65%
    trans-Zeatinriboside is a type of cytokinin precursor, acts as a major long-distance signalling form in xylem vessels, regulates leaf size and meristem activity-related traits.
    trans-Zeatinriboside
  • HY-B1167
    Ajmaline 4360-12-7 99.82%
    Ajmaline (Cardiorythmine) is a sodium channel blocking, class 1A anti-arrhythmic agent. Ajmaline blocks HERG currents with an IC50 of 1 μM in HEK cells and 42.3 μM in Xenopus oocytes. Ajmaline can be used for the research of the ventricular tachyarrhythmia.
    Ajmaline
  • HY-N0252
    Catharanthine 2468-21-5 99.76%
    Catharanthine is an alkaloid isolated from Madagascar periwinkle, inhibits voltage-operated L-type Ca2+ channel, with anti-cancer and blood pressure-lowering activity.
    Catharanthine
  • HY-B1180
    Vinburnine 4880-88-0 99.59%
    Vincamone is a vinca alkaloid and a metabolite of vincamine, is a vasodilator.
    Vinburnine
  • HY-107339
    Deserpidine 131-01-1 98.82%
    Deserpidine (Harmonyl) is an alkaloid isolated from the root of Rauwolfia canescens related to Reserpine. Deserpidine is used as an antihypertensive agent and a tranquilizer. Deserpidine is a competitive angiotensin converting enzyme (ACE) inhibitor. Deserpidine also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex.
    Deserpidine
  • HY-N0480A
    Reserpine hydrochloride 16994-56-2 99.90%
    Reserpine hydrochloride is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).
    Reserpine hydrochloride
  • HY-N8441
    Neriifolin 466-07-9
    Neriifolin, a CNS-penetrating cardiac glycoside, is an inhibitor of the Na+, K+-ATPase. Neriifolin can target beclin 1, inhibits the formation of LC3-associated phagosomes and ameliorates experimental autoimmune encephalomyelitis (EAE) development. Neriifolin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells[2.
    Neriifolin
  • HY-B1021
    Vincamine 1617-90-9 99.76%
    Vincamine is a monoterpenoid indole alkaloid extracted from the Madagascar periwinkle. Vincamine is a peripheral vasodilator and exerts a selective vasoregulator action on the brain microcapilar circulation. Vincamine is a GPR40 agonist and acts as a β-cell protector by ameliorating β-cell dysfunction and promoting glucose-stimulated insulin secretion (GSIS). Vincamine improves glucose homeostasis in vivo, and has the potential for the type 2 diabetes mellitus (T2DM) research.
    Vincamine