- Natural Products
- Plants
- Apocynaceae
- Rauvolfia verticillata (Lour.) Baill.
Rauvolfia verticillata (Lour.) Baill.
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Rauvolfia verticillata (Lour.) Baill. (25)
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- Formula: C33H41ClN2O9
- Molecular Weight: 645.14
Reserpine hydrochloride is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).
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- Formula: C21H22N2O2
- Molecular Weight: 334.41
Vinorine is a compound isolated from the bark of Rauvolfia reflexa.
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- Formula: C12H16O5
- Molecular Weight: 240.25
Ethyl 3,4,5-trimethoxybenzoate is a melanogenesis inhibitor. Ethyl 3,4,5-trimethoxybenzoate does not directly target tyrosinase activity, but inhibits melanin synthesis in a dose-dependent manner by downregulating α-MSH (HY-P0252)-induced tyrosinase protein expression and scavenging ROS. Ethyl 3,4,5-trimethoxybenzoate scavenges DPPH free radicals. Ethyl 3,4,5-trimethoxybenzoate can be used in the research of hyperpigmentation.
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- Formula: C21H28N2O3
- Molecular Weight: 356.46
Rauvoyunine A is a natural alkaloid.
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- Formula: C22H26N2O5
- Molecular Weight: 398.45
11-Methoxyuncarine C (Caboxine B) is a natural alkaloid.
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- Formula: C20H25N2O2+
- Molecular Weight: 325.42
Spegatrine is a Alkaloids product that can be isolated from the roots of Rauvolfia verticillata.
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- Formula: C20H27ClN2O2
- Molecular Weight: 362.89
Ajmaline hydrochloride is a Class Ia antiarrhythmic agent. It inhibits HERG potassium channels with IC50s of 1.0 μmol/l and 42.3 μmol/l in HEK cells and moth spider oocytes respectively. The inhibitory effect of Ajmaline hydrochloride is rapid, reversible, and positive frequency dependent. It acts primarily on the open state of the HERG channel and may also be combined with the inactivated state. The inhibitory effect of ajmaline hydrochloride is dependent on aromatic residues in the S6 domain, and the sensitivity is significantly reduced in the inactivation-deficient HERG S620T channel. It can also slightly affect the activation voltage of HERG channels. Ajmaline hydrochloride's inhibitory effect on HERG channels may contribute to both its potent antiarrhythmic effects and its potential proarrhythmic risk.
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- Formula: C19H22N2O3
- Molecular Weight: 326.39
Rauvovertine B is a hexacyclic monoterpenoid indole alkaloid that can be found in Rauvolfia verticillata.
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- Formula: C20H26N2O3
- Molecular Weight: 342.43
Rauvotetraphylline A is an alkaloid that can be isolated from Rauvolfia tetraphylla.
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- Formula: C21H26N2O3
- Molecular Weight: 354.44
Pelirine is an alkaloid isolated from R. perakensis and causes death in mice at concentrations of 100 mg/kg and above.
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- Formula: C20H24N2O3
- Molecular Weight: 340.42
10-Hydroxy-16-epiaffinine is a natural product that can be isolated from the leaves and twigs of Rauvolfia verticillata.
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- Formula: C12H16O5
- Molecular Weight: 240.25
Ethyl 3,4,5-trimethoxybenzoate is a natural compound isolated from the roots of Rauvolfia yunnanensis Tsiang. Ethyl 3,4,5-trimethoxybenzoate is a melanogenesis inhibitor. Ethyl 3,4,5-trimethoxybenzoate does not directly target tyrosinase activity, but inhibits melanin synthesis in a dose-dependent manner by downregulating α-MSH (HY-P0252)-induced tyrosinase protein expression and scavenging ROS. Ethyl 3,4,5-trimethoxybenzoate scavenges DPPH free radicals. Ethyl 3,4,5-trimethoxybenzoate can be used in the research of hyperpigmentation.
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- Formula: C33H41ClN2O9
- Molecular Weight: 645.14
Reserpine (hydrochloride) (Standard) is the analytical standard of Reserpine (hydrochloride). This product is intended for research and analytical applications. Reserpine hydrochloride is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).
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- Formula: C32H36N2O9
- Molecular Weight: 592.64
Rauvoyunine C is a Alkaloids product that can be isolated from the herbs of Rauvolfia yunnanensis.
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- Formula: C23H26N2O6
- Molecular Weight: 426.46
Rauvoyunine B is a Alkaloids product that can be isolated from the aerial parts of Rauvolfia yunnanensis..
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- Formula: C20H23N3O
- Molecular Weight: 321.42
Rauvovertine C is a Alkaloids product that can be isolated from the stems of Rauvolfia verticillata..
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- Formula: C19H22N2O3
- Molecular Weight: 326.39
Rauvovertine A is a Alkaloids product that can be isolated from the stems of Rauvolfia verticillata..
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